Patrick Dempsey’s new hitman show,Memory of a Killer, casts a star fromThe 100as a series regular. The upcoming drama follows Dempsey’s character, Angelo Ledda, who is a hit man with early-onset Alzheimer’s.Memory of a Killeris set to debut on Fox during the midseason point of the 2025-2026 network television season.

ThePatrick Dempsey showhas also castThe Sopranosstar Michael Imperioli as Dutch, an Italian restaurant owner and chef who runs the criminal organization that employs Angelo. Dutch is also Angelo’s oldest friend.

John Murphy with his faced bruised and cut up and looking menacing in The 100

As perVariety,Memory of a Killerhasnow cast Richard Harmon as a hitman named Joe, who works for Angelo and Dutch. Joe is responsible for reconnaissance and formulating getaway plans while working closely alongside Angelo. This allows him to see firsthand how early-onset Alzheimer’s is affecting Angelo, and Joe must decide what to do with this information.

What This Means For Memory Of A Killer

Memory of a Killerhas added another key character, who is poised to create some of the show’s most riveting conflict. A hitman trying to do his job while dealing with the symptoms of early-onset Alzheimer’s is an intriguing premise, and it becomes more complex with the addition of Joe’s character.

As possibly the only character who knows exactly what is happening to Angelo, Joe has a unique power over him, and has the ability to protect his associate or condemn him to death. Despite Angelo’s longtime friendship with Dutch, the truth would likely mean Angelo’s end, as a hitman with Alzheimer’s is too much of a liability.

As a member ofThe 100’s cast, Harmon’s John Murphy was a recurring role in seasons 1 and 2 before he became a series regular in seasons 1-7. Hewill be playing a more prominent role from the beginning inMemory of a Killer, and will likely be the most important character other than Angelo and Dutch.

Our Take On Memory Of A Killer Casting Richard Harmon

The Series Just Got Even More Intriguing

With John Murphy being arguablyThe 100’s best character, it isexciting to see Harmon taking on another major television role. He had one of the most unpredictable and fascinating arcs inThe 100, and the unique situation Joe finds himself in duringMemory of a Killercan lead to a similarly compelling arc.

The cast and the story have already made the upcoming Fox series one of the most exciting new shows premiering during the upcoming network television season.

Between Dempsey, Imperioli, and now Harmon,Memory of a Killeris assembling an impressive castto bring its strong premise to life. The cast and the story have already made the upcoming Fox series one of the most exciting new shows premiering during the upcoming network television season.